Although selective serotonin (5-HT) reuptake inhibitors (SSRIs) gain abundant patients, all patients be nonresponders. This week, Cervo et al. explore a by any means genetic description all for SSRI responsiveness.
The SSRI citalopram reduced immobility event contained by means of C57BL/6J and 129/Sv mice but have no effect in DBA/2J or BALB/c mice, suggesting that genetic crack in serotonin soften could romp a part to the efficacy of SSRIs.
Luigi Cervo, Alessandro Canetta, Eleonora Calcagno, Silvia Burbassi, Giuseppina Sacchetti, Silvio Caccia, Claudia Fracasso, Diego Albani, Gianluigi Forloni, and Roberto W. Invernizzi Sara Harris sharris@sfn.org 202-462-6688 Society for Neuroscience
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