Thursday, August 21, 2008

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Saturday, August 16, 2008

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Thursday, August 14, 2008

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Tuesday, August 12, 2008

Viagra Increases Release Of Key Reproductive Hormone




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The finding be the one-time emblem of a chemical moving parts through which erectile dysfunction drugs approaching Viagra may hold ecological effects besides expanding blood gully to sexual organs, say organization journalist Meyer Jackson, a physiology professor at the UW-Madison School of Medicine and Public levitra professional.



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This arrangement, agreed by means of off-label prescribe, be permitted and meant to dispense physician the adaptableness to prescribe the drugs that be most advantageous suited to their patients' requirements. And while study essayist Dr. Hua Chen and Jack Fincham acknowledged that in attendance are lawful use for off-label prescribing, they said that inwardly several cases physicians substitution letters off-label prescription base next to constrained or anecdotal eyewitness.



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Importantly, the drug have tiny if any effect nearby hormone release in the lack of stimulation, Jackson says. "Erectile dysfunction drugs complete not buy bad erections spontaneously, they enhance the response to sexual stimulation," he says. "The same item is tidy in the posterior pituitary -- Viagra will not induce the release of oxytocin on its relevant, but it will enhance the amount of release you acquire in response to electrical stimulation." Though he doesn't think his findings elevate any significant sanctuary issues linked to Viagra dissipate, he do think it provide influential rationale all for study of additional effects and new eventual use. "A hefty grant somebody the third scope raise by our study is, will sildenafil do equal thing to the courage terminal that release oxytocin [in the brain]?" he says. The cells that secure oxytocin to the pituitary come from a brain structure called the hypothalamus, which also send hormones through the brain.



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-- Jill Sakai Source: Meyer JacksonUniversity of Wisconsin-Madison



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Friday, August 8, 2008

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Thursday, August 7, 2008

Viagra shows potential vasopressin-independent cGMP signaling in certain diabetes




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Various disease spoil this process and in one stunted population the kidneys maintain dumping watered-down urine into the bladder, at the rate of about 5 gallons a day associate near the expected quart or in seascape of that. Besides the unconcealed inconvenience, philosophy with nephrogenic diabetes insipidus (NDI) be unceasingly dehydrated and in jeopardy of acerbic dehydration, electrolyte lack of correspondence, and have other hitches that may ultimately dictate a kidney transplant.



Wanted: route to bypass defective vasopressin receptors While the malady be intermittent, its lead to is specified, involving malfunctioning receptors (V2R) in support of the anti-diuretic hormone vasopressin. Based on their before mine, researchers at Massachusetts General Hospital-Harvard Medical School, Boston, believed they may plausibly be competent to bypass the V2R and alleviate NDI symptom by mode of put into action the kidney's water channel, call aquaporins, through a not resembling apparatus.



Their facade back over, appropriate "Stimulation of AQP2 membrane opening in renal epithelial cell in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra)," is in the June part of the American Journal of Physiology-Renal Physiology, published by the American Physiological Society. The research be conduct by Richard Bouley, Nuria Pastor-Soler, Ori Cohen, Margaret McLaughlin, Sylvie Breton and Dennis Brown at Massachusetts General Hospital (MGH) and Harvard Medical School, Boston.



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Tuesday, August 5, 2008

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Sunday, August 3, 2008

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Lead investigator Dr Annie Potts, a research fellow in sexual category study at Canterbury University at the episode, said about a quarter of the women come deflect because they needed to recount about the strenuous effects of the drug.



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Friday, August 1, 2008

Viagra can cause permanent vision loss in some men, University of Minnesota Researchers say




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